Research
Published · Updated · 1 min read
Calendula officinalis methanol extract: maximum tyrosinase inhibition was 24.5%
What it means for practice
These findings do not support clinical use of the extract for skin tone correction: its efficacy and safety in clinical settings still require confirmation.
Summary
The study evaluated the potential of Calendula officinalis extracts as natural skin-whitening agents. It examined their phytochemical composition and ability to inhibit tyrosinase. Extracts obtained using chloroform, methanol, and water were compared.
The methanol extract had the highest phenolic and flavonoid content among the extracts studied. Its maximum tyrosinase inhibition was 24.5%. The abstract does not provide corresponding numerical results for the chloroform and water extracts, so their activity cannot be compared quantitatively using the available data.
The authors consider the methanol extract a potentially promising component of cosmetic formulations for skin tone correction. However, they emphasize the need for further research to confirm efficacy and safety in clinical settings. The reported enzyme inhibition should therefore not be interpreted as a demonstrated clinical skin-whitening effect.
The available study abstract does not describe a clinical population, extract concentrations, or the conditions used to measure activity.
Source
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Exploring Calendula officinalis: an in-depth analysis of its potential as a whitening agent.
Reviewed by: DrugCard editorial team ·
This article does not replace clinical judgement. Disclaimer
