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Published · Updated · 1 min read
Autoimmune hepatitis: arthralgia and asthenia as initial manifestations in a case report
What it means for practice
Consider autoimmune hepatitis when arthralgia and asthenia accompany elevated transaminases. The authors emphasize early clinical suspicion and a multidisciplinary approach.
Summary
Presentation and diagnosis
The report describes autoimmune hepatitis in a 55-year-old woman whose initial manifestations were arthralgia and asthenia. Diagnostic investigations revealed elevated transaminases, a positive rheumatoid factor, and specific autoantibodies. A liver biopsy confirmed autoimmune hepatitis. The patient was also diagnosed with an overlap syndrome of autoimmune hepatitis and primary biliary cholangitis.
Treatment and course
High-dose corticosteroid treatment was initiated. Several flare-ups subsequently occurred, but at the time of the report the patient was asymptomatic and remained on immunosuppressive therapy. The abstract does not provide drug names, exact doses, treatment duration, or the follow-up period.
Practical emphasis and scope
The authors emphasize early clinical suspicion and a multidisciplinary approach to managing this condition. The abstract does not specify which autoantibodies were detected, provide numerical laboratory results, or separately discuss limitations of the report. This is a description of the disease course in one patient, not a comparative treatment study.
Source
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Hepatitis autoinmune: artralgias y astenia como síntomas clave.
Reviewed by: DrugCard editorial team ·
This article does not replace clinical judgement. Disclaimer
